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SEPT10
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase |
| Chromosomal Location of mouse Ortholog: 10|10 B4 |
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Cellular Component:
cell division site; cell projection; cilium; cytoplasm; cytoskeleton; microtubule cytoskeleton; motile cilium; septin complex; septin ring; sperm annulus; sperm flagellum
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Molecular Function:
GTP binding; GTPase activity; molecular adaptor activity; nucleotide binding; protein binding
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Biological Process:
cell cycle; cell division; cytoskeleton-dependent cytokinesis
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Reference #:
Q8C650
(UniProtKB)
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Alt. Names/Synonyms: 4921515A04Rik; 9430099J10Rik; AA408298; AI874685; SEP10; Sept; Sept10; septin 10; Septin-10; Septin10
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Gene Symbols: Septin10
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Molecular weight:
52,422 Da
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Basal Isoelectric point:
6.17
Predict pI for various phosphorylation states
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