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L-Myc
a proto-oncogenic transcription factor. Targets include CCL6 chemokine gene. Plays a role in cell proliferation, apoptosis and in the development of human tumors. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding; Oncoprotein; Transcription factor |
| Chromosomal Location of Human Ortholog: 4 D2.2|4 57.36 cM |
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Cellular Component:
nucleus
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Molecular Function:
DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; protein binding; protein dimerization activity; RNA polymerase II proximal promoter sequence-specific DNA binding
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Biological Process:
positive regulation of transcription by RNA polymerase II; regulation of inner ear auditory receptor cell differentiation; regulation of transcription, DNA-templated
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Reference #:
P10166
(UniProtKB)
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Alt. Names/Synonyms: AW536278; bHLHe38; L-myc; L-myc-1 proto-oncogene protein; Lmyc-1; Lmyc1; lung carcinoma myc related oncogene 1; MGC102165; Mycl; Mycl1; OTTMUSP00000009305; OTTMUSP00000009306; Protein L-Myc; Protein L-Myc-1; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
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Gene Symbols: Mycl
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Molecular weight:
40,848 Da
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Basal Isoelectric point:
5.22
Predict pI for various phosphorylation states
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