L-Myc a proto-oncogenic transcription factor. Targets include CCL6 chemokine gene. Plays a role in cell proliferation, apoptosis and in the development of human tumors. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of mouse Ortholog: 4 D2.2|4 57.36 cM
Cellular Component:  chromosome; nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding
Biological Process:  regulation of DNA-templated transcription; regulation of inner ear auditory receptor cell differentiation; regulation of transcription by RNA polymerase II
Reference #:  P10166 (UniProtKB)
Alt. Names/Synonyms: AW536278; bHLHe3; bHLHe38; L-my; L-myc; L-myc-1 proto-oncogene protein; Lmyc; Lmyc-; Lmyc-1; Lmyc1; lung carcinoma myc related oncogene 1; MGC102165; Mycl; Mycl1; OTTMUSP00000009305; OTTMUSP00000009306; Protein L-Myc; Protein L-Myc-1; v-myc avian myelocytomatosis viral oncogene lung carcinoma derived; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian); v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived
Gene Symbols: Mycl
Molecular weight: 40,848 Da
Basal Isoelectric point: 5.22  Predict pI for various phosphorylation states
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L-Myc

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene