CDK10 a CMGC kinase of the CDK family. Plays a role in cellular proliferation. Its function is limited to cell cycle G2-M phase. At least three alternatively spliced isoforms have been reported, two of which contain multiple non-AUG translation initiation sites. Note: This description may include information from UniProtKB.
Protein type: CDK family; CDK/CDK10 subfamily; CDK10 subfamily; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 8|8 E1
Cellular Component:  cell projection; ciliary basal body; cytoplasm; cytoskeleton; nucleus
Molecular Function:  ATP binding; cyclin-dependent protein kinase activity; cyclin-dependent protein serine/threonine kinase activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
Biological Process:  cell projection organization; negative regulation of cilium assembly; peptidyl-threonine phosphorylation; phosphorylation; positive regulation of MAPK cascade; protein phosphorylation; regulation of actin cytoskeleton organization
Reference #:  Q3UMM4 (UniProtKB)
Alt. Names/Synonyms: BC017131; Cdk10; Cell division protein kinase 10; cyclin dependent kinase 10; cyclin-dependent kinase (CDC2-like) 10; Cyclin-dependent kinase 10
Gene Symbols: Cdk10
Molecular weight: 40,961 Da
Basal Isoelectric point: 9.1  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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CDK10

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene