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CDK10
a CMGC kinase of the CDK family. Plays a role in cellular proliferation. Its function is limited to cell cycle G2-M phase. At least three alternatively spliced isoforms have been reported, two of which contain multiple non-AUG translation initiation sites. Note: This description may include information from UniProtKB.
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| Protein type: CDK family; CDK/CDK10 subfamily; CDK10 subfamily; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of Human Ortholog: 8|8 E1 |
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Cellular Component:
cell projection; ciliary basal body; cytoplasm; cytoskeleton; nucleus
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Molecular Function:
ATP binding; cyclin-dependent protein kinase activity; cyclin-dependent protein serine/threonine kinase activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
cell projection organization; negative regulation of cilium assembly; peptidyl-threonine phosphorylation; phosphorylation; positive regulation of MAPK cascade; protein phosphorylation; regulation of actin cytoskeleton organization
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Reference #:
Q3UMM4
(UniProtKB)
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Alt. Names/Synonyms: BC017131; Cdk10; Cell division protein kinase 10; cyclin dependent kinase 10; cyclin-dependent kinase (CDC2-like) 10; Cyclin-dependent kinase 10
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Gene Symbols: Cdk10
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Molecular weight:
40,961 Da
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Basal Isoelectric point:
9.1
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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