SLC25A1 Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation. Belongs to the mitochondrial carrier (TC 2.A.29) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 16 A3|16 11.11 cM
Cellular Component:  integral component of membrane; membrane; mitochondrion
Molecular Function:  transmembrane transporter activity
Biological Process:  mitochondrial citrate transmembrane transport; transmembrane transport
Reference #:  Q8JZU2 (UniProtKB)
Alt. Names/Synonyms: 1300019P08Rik; 2610100G11Rik; AI194714; Ctp; Dgsj; DiGeorge syndrome gene j; MGC47055; Slc20a3; Slc25a1; solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1; solute carrier family 25, member 1; tricarboxylate transport protein; Tricarboxylate transport protein, mitochondrial; TXTP
Gene Symbols: Slc25a1
Molecular weight: 33,931 Da
Basal Isoelectric point: 9.91  Predict pI for various phosphorylation states
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SLC25A1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein