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ENO3
Appears to have a function in striated muscle development and regeneration. Belongs to the enolase family. The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 4.2.1.11; Lyase |
| Chromosomal Location of Human Ortholog: 11 B3|11 43.21 cM |
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Cellular Component:
cytoplasm; cytosol; membrane; phosphopyruvate hydratase complex; plasma membrane
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Molecular Function:
lyase activity; magnesium ion binding; metal ion binding; phosphopyruvate hydratase activity; protein heterodimerization activity; protein homodimerization activity
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Biological Process:
glycolytic process
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Reference #:
P21550
(UniProtKB)
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Alt. Names/Synonyms: 2-phospho-D-glycerate hydro-lyase; Beta-enolase; Eno; Eno-3; Eno3; ENOB; Enolase 3; enolase 3, beta muscle; MSE; Muscle-specific enolase; OTTMUSP00000006349; OTTMUSP00000006350; Skeletal muscle enolase
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Gene Symbols: Eno3
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Molecular weight:
47,025 Da
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Basal Isoelectric point:
6.73
Predict pI for various phosphorylation states
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