ENO3 Appears to have a function in striated muscle development and regeneration. Belongs to the enolase family. The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 4.2.1.11; Lyase
Chromosomal Location of Human Ortholog: 11 B3|11 43.21 cM
Cellular Component:  cytoplasm; cytosol; membrane; phosphopyruvate hydratase complex; plasma membrane
Molecular Function:  lyase activity; magnesium ion binding; metal ion binding; phosphopyruvate hydratase activity; protein heterodimerization activity; protein homodimerization activity
Biological Process:  glycolytic process
Reference #:  P21550 (UniProtKB)
Alt. Names/Synonyms: 2-phospho-D-glycerate hydro-lyase; Beta-enolase; Eno; Eno-3; Eno3; ENOB; Enolase 3; enolase 3, beta muscle; MSE; Muscle-specific enolase; OTTMUSP00000006349; OTTMUSP00000006350; Skeletal muscle enolase
Gene Symbols: Eno3
Molecular weight: 47,025 Da
Basal Isoelectric point: 6.73  Predict pI for various phosphorylation states
Select Structure to View Below

ENO3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene