|
HRC
May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. Belongs to the HRC family. Note: This description may include information from UniProtKB.
|
| Protein type: Calcium-binding; Contractile |
| Chromosomal Location of human Ortholog: 19q13.33 |
|
Cellular Component:
endoplasmic reticulum lumen; sarcoplasmic reticulum lumen; sarcoplasmic reticulum membrane; Z disc
|
|
Molecular Function:
ATPase binding; calcium ion binding; protein binding; transmembrane transporter binding
|
|
Biological Process:
muscle contraction; positive regulation of heart contraction; positive regulation of heart rate; positive regulation of relaxation of cardiac muscle; regulation of calcium ion transmembrane transport; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of cell communication by electrical coupling involved in cardiac conduction; regulation of cytosolic calcium ion concentration; regulation of heart rate; regulation of peptidyl-serine phosphorylation; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; regulation of ryanodine-sensitive calcium-release channel activity
|
|
Reference #:
P23327
(UniProtKB)
|
|
Alt. Names/Synonyms: HCP; histidine rich calcium binding protein; HRC; MGC133236; Sarcoplasmic reticulum histidine-rich calcium-binding protein; SRCH
|
|
Gene Symbols: HRC
|
|
Molecular weight:
80,244 Da
|
|
Basal Isoelectric point:
4.62
Predict pI for various phosphorylation states
|
