HRC May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. Belongs to the HRC family. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Contractile
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component:  endoplasmic reticulum lumen; sarcoplasmic reticulum lumen; Z disc
Molecular Function:  ATPase binding; calcium ion binding; ion channel binding; protein binding
Biological Process:  cellular protein metabolic process; muscle contraction; positive regulation of heart contraction; positive regulation of heart rate; positive regulation of relaxation of cardiac muscle; post-translational protein modification; regulation of calcium ion transmembrane transport; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of cell communication by electrical coupling involved in cardiac conduction; regulation of cytosolic calcium ion concentration; regulation of heart rate; regulation of peptidyl-serine phosphorylation; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; regulation of ryanodine-sensitive calcium-release channel activity
Reference #:  P23327 (UniProtKB)
Alt. Names/Synonyms: HCP; histidine rich calcium binding protein; HRC; MGC133236; Sarcoplasmic reticulum histidine-rich calcium-binding protein; SRCH
Gene Symbols: HRC
Molecular weight: 80,244 Da
Basal Isoelectric point: 4.62  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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