RALGAPB Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB. Highly expressed in brain, mostly in amygdala. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Ras
Chromosomal Location of mouse Ortholog: 2|2 H1
Cellular Component:  cytosol
Molecular Function:  GTPase activator activity; protein heterodimerization activity
Biological Process:  activation of GTPase activity; Ral protein signal transduction; regulation of exocyst localization; regulation of protein localization; regulation of small GTPase mediated signal transduction
Reference #:  Q8BQZ4 (UniProtKB)
Alt. Names/Synonyms: 9330195P16; AI507211; B230339M05Rik; Kiaa1219; mKIAA1219; p170; Ral GTPase activating protein, beta subunit (non-catalytic); ral GTPase-activating protein beta subunit; Ral GTPase-activating protein subunit beta; Ralgapb; RLGPB
Gene Symbols: Ralgapb
Molecular weight: 165,200 Da
Basal Isoelectric point: 6.32  Predict pI for various phosphorylation states
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RALGAPB

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene