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alphaSNBP(A)
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Belongs to the LSM14 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding; Translation |
| Chromosomal Location of mouse Ortholog: 7|7 B1 |
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Cellular Component:
cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytoskeleton; cytosol; mitotic spindle; P-body; ribonucleoprotein complex
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Molecular Function:
double-stranded DNA binding; double-stranded RNA binding; mRNA binding; single-stranded RNA binding
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Biological Process:
defense response to virus; mitotic spindle assembly; multicellular organism development; negative regulation of translation; P-body assembly; positive regulation of type I interferon-mediated signaling pathway; regulation of translation; RIG-I signaling pathway; stress granule assembly
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Reference #:
Q8K2F8
(UniProtKB)
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Alt. Names/Synonyms: 2700023B17Rik; AA407828; alphaSNBP(A); AU017544; Fam61a; LS14A; LSM14 homolog A; LSM14 homolog A (SCD6, S. cerevisiae); Lsm14a; LSM14A mRNA processing body assembly factor; mRAP55A; OTTMUSP00000008737; Protein FAM61A; Protein LSM14 homolog A; Rap55a; RNA-associated protein 55A; Tral
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Gene Symbols: Lsm14a
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Molecular weight:
50,546 Da
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Basal Isoelectric point:
9.55
Predict pI for various phosphorylation states
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