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GATAD2A
Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. Ubiquitous, both in fetal and adult tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of mouse Ortholog: 8|8 B3.3 |
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Cellular Component:
chromosome; nucleoplasm; nucleus; NuRD complex
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Molecular Function:
metal ion binding; protein-macromolecule adaptor activity
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Biological Process:
anterior neuropore closure; blood vessel development; chromatin remodeling; embryonic body morphogenesis; histone deacetylation; in utero embryonic development; negative regulation of DNA-templated transcription; negative regulation of transcription by RNA polymerase II; neural fold formation; positive regulation of DNA-templated transcription; programmed cell death; regulation of cell fate specification; regulation of stem cell differentiation
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Reference #:
Q8CHY6
(UniProtKB)
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Alt. Names/Synonyms: 1110066C11Rik; BC031407; C80248; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; Gatad2a; MGC29315; MGC36975; P66A; Transcriptional repressor p66 alpha
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Gene Symbols: Gatad2a
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Molecular weight:
67,334 Da
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Basal Isoelectric point:
9.91
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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