GATAD2A Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. Ubiquitous, both in fetal and adult tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 8|8 B3.3
Cellular Component:  nucleoplasm; nucleus; NuRD complex
Molecular Function:  metal ion binding; protein binding, bridging
Biological Process:  anterior neuropore closure; blood vessel development; embryonic body morphogenesis; in utero embryonic development; negative regulation of transcription by RNA polymerase II; negative regulation of transcription, DNA-templated; neural fold formation; programmed cell death
Reference #:  Q8CHY6 (UniProtKB)
Alt. Names/Synonyms: 1110066C11Rik; BC031407; C80248; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; Gatad2a; MGC29315; MGC36975; P66A; Transcriptional repressor p66 alpha
Gene Symbols: Gatad2a
Molecular weight: 67,334 Da
Basal Isoelectric point: 9.91  Predict pI for various phosphorylation states
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GATAD2A

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene