ZNF218 Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 2 H3|2 89.47 cM
Cellular Component:  nucleus
Molecular Function:  chromatin binding; DNA binding; metal ion binding; nucleic acid binding; protein binding
Biological Process:  multicellular organism development; regulation of gene expression; regulation of transcription by RNA polymerase II
Reference #:  Q68FE9 (UniProtKB)
Alt. Names/Synonyms: 2900073F20Rik; B830045G17; Kiaa4248; mKIAA4248; Mtsh; Mtsh2; Sdccag; SDCCAG33-like protein; Sdccag33l; serologically defined colon cancer antigen 33 like; teash; teashirt 2; Teashirt homolog 2; teashirt zinc finger family member 2; teashirt2; Tsh; Tsh2; Tshz2; Zfp21; Zfp218; Zinc finger protein 218; Znf218
Gene Symbols: Tshz2
Molecular weight: 114,223 Da
Basal Isoelectric point: 7.53  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene