cytohesin 4
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Expressed predominantly in peripheral blood leukocytes. Note: This description may include information from UniProtKB.
|
Protein type: GEF; GEF, ARF |
Chromosomal Location of Human Ortholog: 15|15 E1 |
Cellular Component:
membrane; plasma membrane
|
Molecular Function:
ARF guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; lipid binding
|
Biological Process:
regulation of ARF protein signal transduction
|
Reference #:
Q80YW0
(UniProtKB)
|
Alt. Names/Synonyms: 2510004M07Rik; 5830469K17Rik; AI467541; CYH4; Cyth4; cytohesin 4; Cytohesin-4; FLJ00017; mFLJ00017; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled/coil domains 4; Psc; Pscd4
|
Gene Symbols: Cyth4
|
Molecular weight:
45,285 Da
|
Basal Isoelectric point:
6.24
Predict pI for various phosphorylation states
|