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cytohesin 4
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Expressed predominantly in peripheral blood leukocytes. Note: This description may include information from UniProtKB.
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| Protein type: GEF; GEF, ARF |
| Chromosomal Location of mouse Ortholog: 15|15 E1 |
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Cellular Component:
membrane; plasma membrane
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Molecular Function:
ARF guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; lipid binding
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Biological Process:
regulation of ARF protein signal transduction
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Reference #:
Q80YW0
(UniProtKB)
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Alt. Names/Synonyms: 2510004M07Rik; 5830469K17Rik; AI467541; CYH4; Cyth4; cytohesin 4; Cytohesin-4; FLJ00017; mFLJ00017; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled/coil domains 4; Psc; Pscd4
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Gene Symbols: Cyth4
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Molecular weight:
45,285 Da
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Basal Isoelectric point:
6.24
Predict pI for various phosphorylation states
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