cytohesin 4 Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Expressed predominantly in peripheral blood leukocytes. Note: This description may include information from UniProtKB.
Protein type: GEF; GEF, ARF
Chromosomal Location of mouse Ortholog: 15|15 E1
Cellular Component:  membrane; plasma membrane
Molecular Function:  ARF guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; lipid binding
Biological Process:  regulation of ARF protein signal transduction
Reference #:  Q80YW0 (UniProtKB)
Alt. Names/Synonyms: 2510004M07Rik; 5830469K17Rik; AI467541; CYH4; Cyth4; cytohesin 4; Cytohesin-4; FLJ00017; mFLJ00017; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled/coil domains 4; Psc; Pscd4
Gene Symbols: Cyth4
Molecular weight: 45,285 Da
Basal Isoelectric point: 6.24  Predict pI for various phosphorylation states
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cytohesin 4

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene