CK1G1 Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Phosphorylates CLSPN. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: CK1 group; CK1 family; EC; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of mouse Ortholog: 9|9 C
Cellular Component:  cytoplasm; cytosol; nucleus; plasma membrane
Molecular Function:  ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
Biological Process:  endocytosis; peptidyl-serine phosphorylation; phosphorylation; positive regulation of canonical Wnt signaling pathway; protein autophosphorylation; protein phosphorylation; signal transduction; Wnt signaling pathway
Reference #:  Q8BTH8 (UniProtKB)
Alt. Names/Synonyms: 9130020E21Rik; casein kinase 1, gamma 1; casein kinase I; Casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK1G1; CKI-gamma 1; Csnk1g1; KC1G1
Gene Symbols: Csnk1g1
Molecular weight: 52,744 Da
Basal Isoelectric point: 9.13  Predict pI for various phosphorylation states
CST Pathways:  Hedgehog Signaling  |  Wnt/ß-Catenin Signaling
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene