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CK1G1
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Phosphorylates CLSPN. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: CK1 group; CK1 family; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of mouse Ortholog: 9|9 C |
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Cellular Component:
cytoplasm; cytosol; nucleus; plasma membrane
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Molecular Function:
ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
endocytosis; peptidyl-serine phosphorylation; phosphorylation; positive regulation of canonical Wnt signaling pathway; protein autophosphorylation; protein phosphorylation; signal transduction; Wnt signaling pathway
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Reference #:
Q8BTH8
(UniProtKB)
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Alt. Names/Synonyms: 9130020E21Rik; casein kinase 1, gamma 1; casein kinase I; Casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK1G1; CKI-gamma 1; Csnk1g1; KC1G1
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Gene Symbols: Csnk1g1
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Molecular weight:
52,744 Da
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Basal Isoelectric point:
9.13
Predict pI for various phosphorylation states
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CST Pathways:
Hedgehog Signaling
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Wnt/ß-Catenin Signaling
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