HSPB8 Displays temperature-dependent chaperone activity. Monomer. Interacts with HSPB1. Interacts with DNAJB6. By 17-beta-estradiol. Predominantly expressed in skeletal muscle and heart. Belongs to the small heat shock protein (HSP20) family. Note: This description may include information from UniProtKB.
Protein type: Heat shock protein
Chromosomal Location of Human Ortholog: 5 F|5 56.41 cM
Cellular Component:  chaperone complex; cytoplasm; cytosol; nucleus
Molecular Function:  identical protein binding; protein binding; protein homodimerization activity
Biological Process:  cellular response to unfolded protein; positive regulation of aggrephagy
Reference #:  Q9JK92 (UniProtKB)
Alt. Names/Synonyms: Alpha-crystallin C chain; AU018630; AW413033; Cryac; crystallin, alpha C; D5Ucla4; E2IG1; H11; H11K; heat shock 27kDa protein 8; heat shock protein 20-like protein; heat shock protein 8; Heat shock protein beta-8; HSP20-like; Hsp22; HspB8; OTTMUSP00000015583; Small stress protein-like protein HSP22
Gene Symbols: Hspb8
Molecular weight: 21,533 Da
Basal Isoelectric point: 4.92  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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HSPB8

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene