AF-4 Belongs to the AF4 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein; Transcription factor
Chromosomal Location of mouse Ortholog: 5 E5|5 50.45 cM
Cellular Component:  ELL-EAF complex; nucleus; transcription elongation factor complex
Molecular Function:  DNA-binding transcription factor activity; double-stranded DNA binding
Biological Process:  positive regulation of transcription, DNA-templated; transcription, DNA-templated
Reference #:  O88573 (UniProtKB)
Alt. Names/Synonyms: 9630032B01Rik; AF-4; Af4; AF4/FMR2 family member 1; AF4/FMR2 family, member 1; Aff1; AW319193; homolog of human MLLT2 unidentified; Mllt; Mllt2; Mllt2h; myeloid/lymphoid or mixed-lineage leukemia translocated to 2 homolog; OTTMUSP00000024781; Protein AF-4; Proto-oncogene AF4; Rob; robotic
Gene Symbols: Aff1
Molecular weight: 131,558 Da
Basal Isoelectric point: 9.4  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene