SREC Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. Endothelial cells. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of mouse Ortholog: 11|11 B5
Cellular Component:  integral component of membrane; membrane
Molecular Function:  low-density lipoprotein particle binding; protein binding; scavenger receptor activity
Biological Process:  cell adhesion; dendrite development; neuron remodeling; positive regulation of axon regeneration; positive regulation of neuron projection development; receptor-mediated endocytosis
Reference #:  Q5ND28 (UniProtKB)
Alt. Names/Synonyms: AA986099; Acetyl LDL receptor; KIAA0149; MGC90792; mKIAA0149; MKIAA0149 protein; OTTMUSP00000006503; Scarf1; Scavenger receptor class F member 1; scavenger receptor class F, member 1; Scavenger receptor expressed by endothelial cells 1 protein; SRE; SREC; SREC-I
Gene Symbols: Scarf1
Molecular weight: 87,464 Da
Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein