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SREC
Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. Endothelial cells. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Membrane protein, integral |
| Chromosomal Location of mouse Ortholog: 11|11 B5 |
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Cellular Component:
membrane; plasma membrane
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Molecular Function:
low-density lipoprotein particle binding; protein binding; scavenger receptor activity
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Biological Process:
cell adhesion; dendrite development; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; neuron remodeling; positive regulation of axon regeneration; positive regulation of neuron projection development
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Reference #:
Q5ND28
(UniProtKB)
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Alt. Names/Synonyms: AA986099; Acetyl LDL receptor; KIAA0149; MGC90792; mKIAA0149; MKIAA0149 protein; OTTMUSP00000006503; Scarf1; Scavenger receptor class F member 1; scavenger receptor class F, member 1; Scavenger receptor expressed by endothelial cells 1 protein; SRE; SREC; SREC-I
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Gene Symbols: Scarf1
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Molecular weight:
87,464 Da
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Basal Isoelectric point:
5.7
Predict pI for various phosphorylation states
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