KIF26A Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity. Belongs to the kinesin-like protein family. KIF26 subfamily. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 12|12 F1
Cellular Component:  cytoplasm; cytoskeleton; kinesin complex; microtubule
Molecular Function:  ATP binding; microtubule binding; microtubule motor activity; nucleotide binding; protein binding
Biological Process:  enteric nervous system development; negative regulation of signal transduction; regulation of cell growth by extracellular stimulus
Reference #:  Q52KG5 (UniProtKB)
Alt. Names/Synonyms: KI26A; Kiaa1236; Kif26a; kinesin family member 26A; Kinesin-like protein KIF26A; mKIAA1236; N-11 kinesin
Gene Symbols: Kif26a
Molecular weight: 196,313 Da
Basal Isoelectric point: 9.01  Predict pI for various phosphorylation states
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KIF26A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein