TAF172 Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner. Belongs to the SNF2/RAD54 helicase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.6.1.-; EC 3.6.4.-; Helicase; Transcription initiation complex
Chromosomal Location of mouse Ortholog: 19|19 C2
Cellular Component:  intracellular membrane-bounded organelle; nucleoplasm
Molecular Function:  ATP-dependent activity, acting on DNA; transcription coregulator activity
Biological Process:  negative regulation of chromatin binding; negative regulation of DNA-templated transcription
Reference #:  E9QAE3 (UniProtKB)
Alt. Names/Synonyms: AI414500; AI447930; B-TFIID TATA-box binding protein associated factor 1; B-TFIID TATA-box-binding protein-associated factor 1; Btaf1; Btaf1 protein; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae); E430027O22Rik; TAF170; TAF172; TATA-binding protein-associated factor 172; TBP-associated factor 170
Gene Symbols: Btaf1
Molecular weight: 207,052 Da
Basal Isoelectric point: 6.01  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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TAF172

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein