TXNDC1 May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Ubiquitous. Highly expressed in kidney, liver, placenta and lung. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12|12 C2
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; integral component of membrane; membrane
Molecular Function:  disulfide oxidoreductase activity
Biological Process:  cell redox homeostasis; oxidation-reduction process; response to endoplasmic reticulum stress
Reference #:  Q8VBT0 (UniProtKB)
Alt. Names/Synonyms: 2810425A04Rik; AI465319; thioredoxin domain containing 1; Thioredoxin domain-containing protein 1; Thioredoxin-related transmembrane protein 1; Tmx1; Txndc; Txndc1
Gene Symbols: Tmx1
Molecular weight: 31,396 Da
Basal Isoelectric point: 5.19  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene