JDP2 a transcriptional coregulator that may play a role in progesterone receptor signaling. a JDP-2 lacks an intrinsic activation domain and interacts directly with other coactivators including CBP and pCAF. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 12|12 D2
Cellular Component:  nucleus
Molecular Function:  chromatin binding; DNA binding; DNA-binding transcription factor activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; double-stranded DNA binding; protein binding; protein heterodimerization activity; RNA polymerase II proximal promoter sequence-specific DNA binding; transcription corepressor activity
Biological Process:  negative regulation of fat cell differentiation; negative regulation of transcription by RNA polymerase II; positive regulation of histone deacetylation; regulation of histone deacetylation; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  P97875 (UniProtKB)
Alt. Names/Synonyms: Jdp2; Jun dimerization protein 2; Jundm2; Jundp2; TIF
Gene Symbols: Jdp2
Molecular weight: 18,675 Da
Basal Isoelectric point: 9.32  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  NURSA