SP4 Binds to GT and GC boxes promoters elements. Probable transcriptional activator. Belongs to the Sp1 C2H2-type zinc-finger protein family. Abundant in brain. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 12 F2|12 63.48 cM
Cellular Component:  cytosol; nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; nucleic acid binding; sequence-specific DNA binding; transcription coactivator activity
Biological Process:  regulation of heart contraction; regulation of transcription by RNA polymerase II
Reference #:  Q62445 (UniProtKB)
Alt. Names/Synonyms: 5730497N03Rik; HF-1b; HF1-b; Sp4; trans-acting transcription factor 4; Transcription factor Sp4
Gene Symbols: Sp4
Molecular weight: 81,906 Da
Basal Isoelectric point: 6.65  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene