RFX1 Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. Belongs to the RFX family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 8 C2|8 40.28 cM
Cellular Component:  intracellular membrane-bounded organelle; nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding
Biological Process:  regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  P48377 (UniProtKB)
Alt. Names/Synonyms: AI047719; AI385641; MHC class II regulatory factor RFX1; Regulatory factor X 1; regulatory factor X, 1 (influences HLA class II expression); Rfx1; Transcription factor RFX1; vregulatory factor X, 1 (influences HLA class II expression)
Gene Symbols: Rfx1
Molecular weight: 103,707 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein