FAM83B Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades. Belongs to the FAM83 family. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 6p12.1
Cellular Component:  cytoplasm; membrane
Molecular Function:  epidermal growth factor receptor binding; phosphatidylinositol 3-kinase catalytic subunit binding; phosphatidylinositol 3-kinase regulatory subunit binding; protein kinase binding
Biological Process:  cell proliferation; epidermal growth factor receptor signaling pathway
Reference #:  Q5T0W9 (UniProtKB)
Alt. Names/Synonyms: C6orf143; FA83B; FAM83B; family with sequence similarity 83 member B; family with sequence similarity 83, member B; FLJ30642; hypothetical protein LOC222584; MGC126677; MGC138480; Protein FAM83B
Gene Symbols: FAM83B
Molecular weight: 114,799 Da
Basal Isoelectric point: 9.04  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene