VPS45A May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. Belongs to the STXBP/unc-18/SEC1 family. Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 3 F2.1|3 41.65 cM
Cellular Component:  endosome; endosome membrane; Golgi apparatus; Golgi membrane; integral component of membrane; membrane; synaptic vesicle
Molecular Function:  protein binding
Biological Process:  protein transport; vesicle docking involved in exocytosis; vesicle-mediated transport
Reference #:  P97390 (UniProtKB)
Alt. Names/Synonyms: AI462172; AW554165; mVp; mVps45; OTTMUSP00000025032; vacuolar protein sorting 45; vacuolar protein sorting 45 (yeast); vacuolar protein sorting protein 45; Vacuolar protein sorting-associated protein 45; Vps45; Vps45a
Gene Symbols: Vps45
Molecular weight: 65,053 Da
Basal Isoelectric point: 8.42  Predict pI for various phosphorylation states
Select Structure to View Below

VPS45A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene