DPP10 Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. Belongs to the peptidase S9B family. DPPIV subfamily. Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of human Ortholog: 2q14.1
Cellular Component:  membrane; plasma membrane; voltage-gated potassium channel complex
Molecular Function:  ion channel binding; potassium channel regulator activity; serine-type peptidase activity
Biological Process:  positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; proteolysis; regulation of potassium ion transmembrane transport
Reference #:  Q8N608 (UniProtKB)
Alt. Names/Synonyms: dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; dipeptidyl peptidase like 10; dipeptidyl peptidase like protein 2; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10; dipeptidyl-peptidase 10 (inactive); dipeptidyl-peptidase 10 (non-functional); DPL2; DPP X; DPP10; DPPY; DPRP-3; DPRP3; Inactive dipeptidyl peptidase 10; KIAA1492
Gene Symbols: DPP10
Molecular weight: 90,888 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  Ensembl Protein