GPC5 Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver. Note: This description may include information from UniProtKB.
Protein type: Cell surface; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 13q31.3
Cellular Component:  anchored component of plasma membrane; collagen-containing extracellular matrix; extracellular region; extracellular space; Golgi lumen; integral component of membrane; lysosomal lumen; plasma membrane
Biological Process:  glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; regulation of signal transduction; retinoid metabolic process
Reference #:  P78333 (UniProtKB)
Alt. Names/Synonyms: bA93M14.1; glypican 5; glypican proteoglycan 5; Glypican-5; GPC5; Secreted glypican-5
Gene Symbols: GPC5
Molecular weight: 63,707 Da
Basal Isoelectric point: 6.38  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene