|
K15
Belongs to the intermediate filament family. Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Cytoskeletal |
| Chromosomal Location of human Ortholog: 17q21.2 |
|
Cellular Component:
cytoskeleton; cytosol; intermediate filament
|
|
Molecular Function:
protein binding; scaffold protein binding; structural constituent of cytoskeleton
|
|
Biological Process:
epidermis development; epithelial cell differentiation; intermediate filament organization
|
|
Reference #:
P19012
(UniProtKB)
|
|
Alt. Names/Synonyms: CK-15; CK15; cytokeratin 15; Cytokeratin-15; K15; K1C15; K1CO; keratin 15; keratin 15, type I; Keratin, type I cytoskeletal 15; Keratin-15; keratin-15, basic; keratin-15, beta; KRT15; KRTB; type I cytoskeletal 15
|
|
Gene Symbols: KRT15
|
|
Molecular weight:
49,212 Da
|
|
Basal Isoelectric point:
4.71
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
