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MYCT1
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. Belongs to the MYCT1 family. Down-regulated in gastric cancer tissues. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of human Ortholog: 6q25.2 |
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Cellular Component:
intracellular membrane-bounded organelle; nucleoplasm
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Biological Process:
hematopoietic stem cell homeostasis
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Reference #:
Q8N699
(UniProtKB)
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Alt. Names/Synonyms: FLJ21269; MGC156309; MGC156310; MTLC; MTMC1; myc target 1; myc target in myeloid cells 1; Myc target in myeloid cells protein 1; Myc target protein 1; MYCT1
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Gene Symbols: MYCT1
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Molecular weight:
26,593 Da
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Basal Isoelectric point:
9.88
Predict pI for various phosphorylation states
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