NIBP Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Belongs to the NIBP family. Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Activator
Chromosomal Location of mouse Ortholog: 15|15 D3
Cellular Component:  cytoplasm; early endosome; endoplasmic reticulum; Golgi apparatus; late endosome; trans-Golgi network; TRAPP complex; TRAPPII protein complex
Molecular Function:  protein binding
Biological Process:  cell differentiation; cerebral cortex development; endoplasmic reticulum to Golgi vesicle-mediated transport; neuron differentiation; positive regulation of NF-kappaB transcription factor activity; vesicle coating; vesicle tethering
Reference #:  Q3U0M1 (UniProtKB)
Alt. Names/Synonyms: 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; Ibp; Ikk2 binding protein; Kiaa1882; mKIAA1882; Nibp; NIK and IKK(beta) binding protein; NIK- and IKBKB-binding protein; TPPC9; trafficking protein particle complex 9; Trafficking protein particle complex subunit 9; Trappc9; TRS1; TRS130
Gene Symbols: Trappc9
Molecular weight: 128,232 Da
Basal Isoelectric point: 6.03  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene