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NIBP
Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Belongs to the NIBP family. Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Activator |
| Chromosomal Location of mouse Ortholog: 15|15 D3 |
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Cellular Component:
cytoplasm; early endosome; endoplasmic reticulum; Golgi apparatus; late endosome; trans-Golgi network; TRAPP complex; TRAPPII protein complex
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Molecular Function:
protein binding
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Biological Process:
cell differentiation; cerebral cortex development; endoplasmic reticulum to Golgi vesicle-mediated transport; neuron differentiation; positive regulation of NF-kappaB transcription factor activity; vesicle coating; vesicle tethering
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Reference #:
Q3U0M1
(UniProtKB)
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Alt. Names/Synonyms: 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; Ibp; Ikk2 binding protein; Kiaa1882; mKIAA1882; Nibp; NIK and IKK(beta) binding protein; NIK- and IKBKB-binding protein; TPPC9; trafficking protein particle complex 9; Trafficking protein particle complex subunit 9; Trappc9; TRS1; TRS130
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Gene Symbols: Trappc9
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Molecular weight:
128,232 Da
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Basal Isoelectric point:
6.03
Predict pI for various phosphorylation states
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