SHF Adapter protein which may play a role in the regulation of apoptosis in response to PDGF. Expressed in skeletal muscle, brain, liver, prostate, testis, ovary, small intestine and colon. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 15q21.1
Cellular Component: 
Biological Process:  apoptotic process
Reference #:  Q7M4L6 (UniProtKB)
Alt. Names/Synonyms: cDNA FLJ37072 fis, clone BRACE2015412, weakly similar to Shb=Src homology 2 protein; MGC126650; MGC126652; SH2 domain-containing adapter protein F; SHF; SHF protein; Src homology 2 domain containing F; Src homology 2 domain containing F, isoform CRA_b
Gene Symbols: SHF
Molecular weight: 46,768 Da
Basal Isoelectric point: 6.01  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB