TTYH3 Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. Belongs to the tweety family. Expressed in excitable tissues. Expressed in the brain, heart, skeletal muscle, colon, spleen, kidney and peripheral blood leukocytes. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, chloride; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel
Chromosomal Location of mouse Ortholog: 5|5 G2
Cellular Component:  chloride channel complex; membrane; plasma membrane
Molecular Function:  chloride channel activity; intracellular calcium activated chloride channel activity; volume-sensitive chloride channel activity
Biological Process:  chloride transport; ion transport
Reference #:  Q6P5F7 (UniProtKB)
Alt. Names/Synonyms: 2900029G13Rik; AI414930; Kiaa1691; mTTY3; Protein tweety homolog 3; TTY3; Ttyh3; tweety family member 3; tweety homolog 3; tweety homolog 3 (Drosophila)
Gene Symbols: Ttyh3
Molecular weight: 57,714 Da
Basal Isoelectric point: 5.52  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene