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TTYH3
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. Belongs to the tweety family. Expressed in excitable tissues. Expressed in the brain, heart, skeletal muscle, colon, spleen, kidney and peripheral blood leukocytes. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Channel, chloride; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel |
| Chromosomal Location of mouse Ortholog: 5|5 G2 |
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Cellular Component:
chloride channel complex; membrane; plasma membrane
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Molecular Function:
chloride channel activity; intracellular calcium activated chloride channel activity; volume-sensitive chloride channel activity
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Biological Process:
chloride transport; ion transport
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Reference #:
Q6P5F7
(UniProtKB)
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Alt. Names/Synonyms: 2900029G13Rik; AI414930; Kiaa1691; mTTY3; Protein tweety homolog 3; TTY3; Ttyh3; tweety family member 3; tweety homolog 3; tweety homolog 3 (Drosophila)
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Gene Symbols: Ttyh3
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Molecular weight:
57,714 Da
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Basal Isoelectric point:
5.52
Predict pI for various phosphorylation states
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