CDC42EP3 Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Belongs to the BORG/CEP family. Highly expressed in the heart and weakly in the brain. Note: This description may include information from UniProtKB.
Protein type: G protein regulator, misc.
Chromosomal Location of Human Ortholog: 2p22.2
Cellular Component:  actin cytoskeleton; cytosol; endomembrane system; plasma membrane
Molecular Function:  cytoskeletal regulatory protein binding; protein binding
Biological Process:  signal transduction
Reference #:  Q9UKI2 (UniProtKB)
Alt. Names/Synonyms: Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CDC42EP3; CEP3; CRIB-containing BORG2 protein; FLJ46903; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1
Gene Symbols: CDC42EP3
Molecular weight: 27,678 Da
Basal Isoelectric point: 5.49  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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