SMAP1L GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, ARF
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component:  cytoplasm
Molecular Function:  GTPase activator activity; metal ion binding; protein binding
Biological Process:  positive regulation of GTPase activity
Reference #:  Q8WU79 (UniProtKB)
Alt. Names/Synonyms: RP1-228H13.3; small ArfGAP2; SMAP1L; SMAP2; stromal membrane-associated GTPase-activating protein 2; Stromal membrane-associated protein 1-like; Stromal membrane-associated protein 2
Gene Symbols: SMAP2
Molecular weight: 46,786 Da
Basal Isoelectric point: 9.01  Predict pI for various phosphorylation states
Select Structure to View Below

SMAP1L

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein