SAPAP2 May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. Expressed in brain and kidney. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Kinase, other
Chromosomal Location of Human Ortholog: 8p23.3
Cellular Component:  cell junction; neurofilament; plasma membrane; postsynaptic density; postsynaptic membrane
Molecular Function:  protein binding
Biological Process:  neuron-neuron synaptic transmission
Reference #:  Q9P1A6 (UniProtKB)
Alt. Names/Synonyms: DAP-2; DAP2; discs, large (Drosophila) homolog-associated protein 2; Disks large-associated protein 2; DLGAP2; DLGP2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2
Gene Symbols: DLGAP2
Molecular weight: 117,620 Da
Basal Isoelectric point: 6.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB