STMN3 Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. Belongs to the stathmin family. Neuron specific. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of human Ortholog: 20q13.33
Cellular Component:  cytoplasm; cytosol; Golgi apparatus; growth cone; neuron projection
Molecular Function:  protein binding; protein domain specific binding; tubulin binding
Biological Process:  blastocyst hatching; cytoplasmic microtubule organization; microtubule depolymerization; negative regulation of Rac protein signal transduction; nervous system development; neuron projection development; regulation of cytoskeleton organization; regulation of GTPase activity; regulation of microtubule polymerization or depolymerization
Reference #:  Q9NZ72 (UniProtKB)
Alt. Names/Synonyms: SCG10-like protein; SCG10-like-protein; SCLIP; stathmin 3; Stathmin-3; stathmin-like 3; STMN3
Gene Symbols: STMN3
Molecular weight: 21,017 Da
Basal Isoelectric point: 6.99  Predict pI for various phosphorylation states
CST Pathways:  Microtubule Dynamics
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene