SYBU Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q23.2
Cellular Component:  axon cytoplasm; cytoplasmic vesicle; dense body; Golgi membrane; integral component of membrane; intracellular membrane-bounded organelle
Molecular Function:  kinesin binding; microtubule binding; protein binding; syntaxin-1 binding
Biological Process:  anterograde neuronal dense core vesicle transport; axonal transport of mitochondrion; positive regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of synaptic activity; synapse maturation
Reference #:  Q9NX95 (UniProtKB)
Alt. Names/Synonyms: FLJ20366; Golgi-localized protein; Golgi-localized syntaphilin-related protein; GOLSYN; GOLSYN A protein; GOLSYN B protein; GOLSYN C protein; implicated in syntaxin trafficking in neurons; KIAA1472; SYBU; Syntabulin; Syntaxin-1-binding protein
Gene Symbols: SYBU
Molecular weight: 72,388 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein