enamelin Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. Expressed in tooth particularly in odontoblast, ameloblast and cementoblast. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 4q13.3
Cellular Component:  endoplasmic reticulum lumen
Molecular Function:  protein binding
Biological Process:  biomineral tissue development; cellular protein metabolic process; post-translational protein modification; regulation of cell morphogenesis
Disease: Amelogenesis Imperfecta, Type Ib; Amelogenesis Imperfecta, Type Ic
Reference #:  Q9NRM1 (UniProtKB)
Alt. Names/Synonyms: ADAI; AI1C; AIH2; amelogenesis imperfecta 2, hypocalcification (autosomal dominant); ENAM; Enamelin
Gene Symbols: ENAM
Molecular weight: 128,785 Da
Basal Isoelectric point: 6.36  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB