enamelin Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. Expressed in tooth particularly in odontoblast, ameloblast and cementoblast. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 4q13.3
Cellular Component:  endoplasmic reticulum lumen; extracellular matrix; extracellular region
Molecular Function:  protein binding; structural constituent of tooth enamel
Biological Process:  ameloblast differentiation; amelogenesis; biomineral tissue development; positive regulation of enamel mineralization
Disease: Amelogenesis Imperfecta, Type Ib; Amelogenesis Imperfecta, Type Ic
Reference #:  Q9NRM1 (UniProtKB)
Alt. Names/Synonyms: ADAI; AI1C; AIH2; amelogenesis imperfecta 2, hypocalcification (autosomal dominant); ENAM; Enamelin
Gene Symbols: ENAM
Molecular weight: 128,785 Da
Basal Isoelectric point: 6.36  Predict pI for various phosphorylation states
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enamelin

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein