ZNF830 May play a role in pre-mRNA splicing as component of the spliceosome. Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17q12
Cellular Component:  chromosome; nuclear speck; nucleoplasm; spliceosomal complex
Molecular Function:  nucleic acid binding; protein binding; zinc ion binding
Biological Process:  blastocyst growth; cell division; chromosome organization; intestinal epithelial structure maintenance; mitotic DNA replication checkpoint; mRNA processing; negative regulation of apoptotic process; ovarian follicle development; preantral ovarian follicle growth; replication fork protection; RNA splicing; transcription-coupled nucleotide-excision repair
Reference #:  Q96NB3 (UniProtKB)
Alt. Names/Synonyms: CCDC16; coiled-coil domain containing 16; Coiled-coil domain-containing protein 16; hypothetical protein MGC20398; MGC20398; OMCG1; orphan maintenance of genome 1; sel-13 suppressor of lin-12 homolog; SEL13; Zinc finger protein 830; ZN830; ZNF830
Gene Symbols: ZNF830
Molecular weight: 41,999 Da
Basal Isoelectric point: 5.22  Predict pI for various phosphorylation states
Select Structure to View Below

ZNF830

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein