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EAF1
Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Belongs to the EAF family. Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of human Ortholog: 3p25.1 |
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Cellular Component:
Cajal body; intercellular bridge; intracellular membrane-bounded organelle; nuclear body; nuclear speck; nucleoplasm; super elongation complex; transcription elongation factor complex
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Molecular Function:
protein binding; transcription elongation factor activity
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Biological Process:
regulation of transcription elongation by RNA polymerase II; transcription elongation by RNA polymerase II
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Reference #:
Q96JC9
(UniProtKB)
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Alt. Names/Synonyms: EAF1; ELL (eleven nineteen lysine-rich leukemia gene)-associated factor 1; ELL associated factor 1; ELL-associated factor 1
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Gene Symbols: EAF1
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Molecular weight:
29,042 Da
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Basal Isoelectric point:
5.24
Predict pI for various phosphorylation states
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