EXOC8 Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the EXO84 family. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 1q42.2
Cellular Component:  cell leading edge; cytosol; exocyst; growth cone; late endosome; perinuclear region of cytoplasm; plasma membrane
Molecular Function:  protein binding; Ral GTPase binding
Biological Process:  endosome organization; extracellular matrix disassembly; protein transport; regulation of macroautophagy
Disease: Neurodevelopmental Disorder With Microcephaly, Seizures, And Brain Atrophy
Reference #:  Q8IYI6 (UniProtKB)
Alt. Names/Synonyms: EXO84; Exo84p; EXOC8; Exocyst complex 84 kDa subunit; exocyst complex 84-kDa subunit; Exocyst complex component 8; SEC84
Gene Symbols: EXOC8
Molecular weight: 81,799 Da
Basal Isoelectric point: 5.35  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene