DPP8
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Belongs to the peptidase S9B family. DPPIV subfamily. Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 3.4.14.5; Protease |
Chromosomal Location of human Ortholog: 15q22.31 |
Cellular Component:
cytoplasm; cytosol
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Molecular Function:
aminopeptidase activity; dipeptidyl-peptidase activity; protein binding; serine-type peptidase activity
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Biological Process:
apoptotic process; immune response; negative regulation of programmed cell death; proteolysis
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Reference #:
Q6V1X1
(UniProtKB)
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Alt. Names/Synonyms: Dipeptidyl peptidase 8; Dipeptidyl peptidase IV-related protein 1; dipeptidyl peptidase IV-related protein-1; Dipeptidyl peptidase VIII; dipeptidyl-peptidase 8; dipeptidylpeptidase 8; DP8; DPP VIII; DPP8; DPRP-1; DPRP1; FLJ14920; FLJ20283; MGC26191; MST097; MSTP097; MSTP135; MSTP141; Prolyl dipeptidase DPP8
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Gene Symbols: DPP8
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Molecular weight:
103,358 Da
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Basal Isoelectric point:
5.52
Predict pI for various phosphorylation states
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