DPP8 Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Belongs to the peptidase S9B family. DPPIV subfamily. Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Protease
Chromosomal Location of human Ortholog: 15q22.31
Cellular Component:  cytoplasm; cytosol
Molecular Function:  aminopeptidase activity; dipeptidyl-peptidase activity; protein binding; serine-type peptidase activity
Biological Process:  apoptotic process; immune response; negative regulation of programmed cell death; proteolysis
Reference #:  Q6V1X1 (UniProtKB)
Alt. Names/Synonyms: Dipeptidyl peptidase 8; Dipeptidyl peptidase IV-related protein 1; dipeptidyl peptidase IV-related protein-1; Dipeptidyl peptidase VIII; dipeptidyl-peptidase 8; dipeptidylpeptidase 8; DP8; DPP VIII; DPP8; DPRP-1; DPRP1; FLJ14920; FLJ20283; MGC26191; MST097; MSTP097; MSTP135; MSTP141; Prolyl dipeptidase DPP8
Gene Symbols: DPP8
Molecular weight: 103,358 Da
Basal Isoelectric point: 5.52  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein