ARHGEF10L Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. Detected in heart, liver, skeletal muscle, kidney and pancreas. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Deacetylase; GEF; GEF, Rac/Rho; Transcription, coactivator/corepressor
Chromosomal Location of human Ortholog: 1p36.13
Cellular Component:  cytosol
Molecular Function:  GTPase activator activity; guanyl-nucleotide exchange factor activity
Biological Process:  actin cytoskeleton organization; positive regulation of stress fiber assembly; regulation of small GTPase mediated signal transduction; SREBP signaling pathway
Reference #:  Q9HCE6 (UniProtKB)
Alt. Names/Synonyms: ARGAL; ARHGEF10L; FLJ10521; GRINCHGEF; KIAA1626; Rho guanine nucleotide exchange factor (GEF) 10-like; Rho guanine nucleotide exchange factor 10 like; Rho guanine nucleotide exchange factor 10-like protein; RP11-473A10.1
Gene Symbols: ARHGEF10L
Molecular weight: 140,379 Da
Basal Isoelectric point: 5.62  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene