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RNPC2
Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1. May be involved in pre-mRNA splicing process. Belongs to the splicing factor SR family. Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Nuclear receptor co-regulator; RNA-binding; Spliceosome |
| Chromosomal Location of human Ortholog: 20q11.22 |
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Cellular Component:
centriolar satellite; microtubule cytoskeleton; nuclear speck; nucleoplasm; protein-containing complex
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Molecular Function:
protein binding; RS domain binding; U1 snRNP binding
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Biological Process:
mRNA processing; regulation of mRNA splicing, via spliceosome; RNA processing; RNA splicing
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Reference #:
Q14498
(UniProtKB)
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Alt. Names/Synonyms: CAPER; CAPER alpha; CAPERalpha; CC1.3; coactivator of activating protein-1 and estrogen receptors; DKFZp781C0423; epididymis secretory sperm binding protein; FLJ44170; fSAP59; functional spliceosome-associated protein 59; HCC1; Hepatocellular carcinoma protein 1; RBM39; RNA binding motif protein 39; RNA-binding motif protein 39; RNA-binding protein 39; RNA-binding region (RNP1, RRM) containing 2; RNA-binding region-containing protein 2; RNPC2; splicing factor CC1.3; Splicing factor HCC1
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Gene Symbols: RBM39
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Molecular weight:
59,380 Da
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Basal Isoelectric point:
10.1
Predict pI for various phosphorylation states
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