CDC42EP1 Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. Belongs to the BORG/CEP family. Endothelial and bone marrow stromal cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of human Ortholog: 22q13.1
Cellular Component:  cytoplasm; cytoskeleton; cytosol; endomembrane system; plasma membrane
Molecular Function:  protein binding
Biological Process:  cell-cell adhesion; positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; regulation of cell shape; Rho protein signal transduction
Reference #:  Q00587 (UniProtKB)
Alt. Names/Synonyms: 55 kDa bone marrow stromal/endothelial cell protein; Binder of Rho GTPases 5; BORG5; CDC42 effector protein (Rho GTPase binding) 1; Cdc42 effector protein 1; CDC42EP1; CEP1; MGC15316; MSE55; serum constituent protein; Serum protein MSE55
Gene Symbols: CDC42EP1
Molecular weight: 40,295 Da
Basal Isoelectric point: 6.64  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB