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CDC42EP1
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. Belongs to the BORG/CEP family. Endothelial and bone marrow stromal cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GAP; GAP, Rac/Rho |
| Chromosomal Location of human Ortholog: 22q13.1 |
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Cellular Component:
cytoplasm; cytoskeleton; cytosol; endomembrane system; plasma membrane
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Molecular Function:
protein binding; small GTPase binding
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Biological Process:
cell-cell adhesion; positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; regulation of cell shape; Rho protein signal transduction
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Reference #:
Q00587
(UniProtKB)
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Alt. Names/Synonyms: 55 kDa bone marrow stromal/endothelial cell protein; Binder of Rho GTPases 5; BORG5; CDC42 effector protein (Rho GTPase binding) 1; Cdc42 effector protein 1; CDC42EP1; CEP1; MGC15316; MSE55; serum constituent protein; Serum protein MSE55
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Gene Symbols: CDC42EP1
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Molecular weight:
40,295 Da
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Basal Isoelectric point:
6.64
Predict pI for various phosphorylation states
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