MTIF2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. Belongs to the IF-2 family. Note: This description may include information from UniProtKB.
Protein type: Mitochondrial; Translation; Translation initiation
Chromosomal Location of Human Ortholog: 2p16.1
Cellular Component:  mitochondrion; nucleoplasm
Molecular Function:  GTP binding; GTPase activity; ribosomal small subunit binding; translation factor activity, RNA binding; translation initiation factor activity
Biological Process:  mitochondrial translational initiation; regulation of translational initiation; ribosome disassembly
Reference #:  P46199 (UniProtKB)
Alt. Names/Synonyms: IF-2(Mt); IF-2Mt; IF2(mt); IF2M; mitochondrial translational initiation factor 2; MTIF2; Translation initiation factor IF-2, mitochondrial
Gene Symbols: MTIF2
Molecular weight: 81,317 Da
Basal Isoelectric point: 6.71  Predict pI for various phosphorylation states
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MTIF2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein