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SAPAP3
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold; Membrane protein, peripheral |
| Chromosomal Location of Human Ortholog: 1p34.3 |
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Cellular Component:
cell junction; cholinergic synapse; glutamatergic synapse; neuromuscular junction; plasma membrane; postsynaptic density; postsynaptic membrane
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Molecular Function:
amyloid-beta binding; protein binding
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Biological Process:
modification of synaptic structure; signaling
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Reference #:
O95886
(UniProtKB)
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Alt. Names/Synonyms: DAP-3; DAP3; discs large homolog associated protein 3; discs, large (Drosophila) homolog-associated protein 3; Disks large-associated protein 3; DLG associated protein 3; DLGAP3; DLGP3; PSD-95/SAP90-binding protein 3; SAP90/PSD 95 associated protein 3; SAP90/PSD-95-associated protein 3; SAPAP3
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Gene Symbols: DLGAP3
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Molecular weight:
106,040 Da
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Basal Isoelectric point:
8.99
Predict pI for various phosphorylation states
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