SAPAP3 May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Membrane protein, peripheral
Chromosomal Location of Human Ortholog: 1p34.3
Cellular Component:  cell junction; cholinergic synapse; glutamatergic synapse; neuromuscular junction; plasma membrane; postsynaptic density; postsynaptic membrane
Molecular Function:  amyloid-beta binding; protein binding
Biological Process:  modification of synaptic structure; signaling
Reference #:  O95886 (UniProtKB)
Alt. Names/Synonyms: DAP-3; DAP3; discs large homolog associated protein 3; discs, large (Drosophila) homolog-associated protein 3; Disks large-associated protein 3; DLG associated protein 3; DLGAP3; DLGP3; PSD-95/SAP90-binding protein 3; SAP90/PSD 95 associated protein 3; SAP90/PSD-95-associated protein 3; SAPAP3
Gene Symbols: DLGAP3
Molecular weight: 106,040 Da
Basal Isoelectric point: 8.99  Predict pI for various phosphorylation states
Select Structure to View Below

SAPAP3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene