SAPS2 Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Belongs to the SAPS family. Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 22q13.33
Cellular Component:  cytosol; intracellular membrane-bounded organelle
Molecular Function:  protein binding
Reference #:  O75170 (UniProtKB)
Alt. Names/Synonyms: dJ579N16.1; KIAA0685; PP6R2; PPP6R2; protein phosphatase 6 regulatory subunit 2; SAP190; SAPS domain family member 2; SAPS domain family, member 2; SAPS2; Serine/threonine-protein phosphatase 6 regulatory subunit 2
Gene Symbols: PPP6R2
Molecular weight: 104,942 Da
Basal Isoelectric point: 4.74  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein