SNAP-91 Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats. Belongs to the PICALM/SNAP91 family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 6q14.2
Cellular Component: 
Molecular Function:  protein binding; protein kinase binding
Biological Process:  clathrin coat assembly; protein transport; regulation of clathrin-dependent endocytosis
Reference #:  O60641 (UniProtKB)
Alt. Names/Synonyms: 91 kDa synaptosomal-associated protein; AP180; assembly protein, 180kDa; CALM; Clathrin coat assembly protein AP180; Clathrin coat-associated protein AP180; DKFZp781O0519; KIAA0656; Phosphoprotein F1-20; SNAP-91; SNAP91; synaptosomal-associated protein, 91kDa homolog; synaptosomal-associated protein, 91kDa homolog (mouse); synaptosome associated protein 91; synaptosome associated protein 91kDa
Gene Symbols: SNAP91
Molecular weight: 92,502 Da
Basal Isoelectric point: 4.69  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene