AGPS Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. Note: This description may include information from UniProtKB.
Protein type: EC; Lipid Metabolism - ether lipid; Mitochondrial; Oxidoreductase; Transferase
Chromosomal Location of Human Ortholog: 2q31.2
Cellular Component:  cytosol; nucleolus; peroxisomal matrix; peroxisome
Molecular Function:  alkylglycerone-phosphate synthase activity; FAD binding; oxidoreductase activity; protein binding
Biological Process:  ether lipid biosynthetic process; lipid biosynthetic process; oxidation-reduction process; protein targeting to peroxisome
Disease: Rhizomelic Chondrodysplasia Punctata, Type 3
Reference #:  O00116 (UniProtKB)
Alt. Names/Synonyms: ADAP-S; ADAS; ADHAPS; ADPS; Aging-associated gene 5 protein; aging-associated protein 5; AGPS; ALDHPSY; Alkyl-DHAP synthase; alkyldihydroxyacetone phosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; alkylglycerone phosphate synthase; Alkylglycerone-phosphate synthase; DKFZp762O2215; FLJ99755
Gene Symbols: AGPS
Molecular weight: 72,912 Da
Basal Isoelectric point: 6.99  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene