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AGPS
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.5.1.26; Lipid Metabolism - ether lipid; Mitochondrial; Oxidoreductase; Transferase |
| Chromosomal Location of human Ortholog: 2q31.2 |
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Cellular Component:
cytosol; peroxisomal matrix; peroxisome
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Molecular Function:
alkylglycerone-phosphate synthase activity; FAD binding; protein binding
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Biological Process:
ether lipid biosynthetic process; lipid biosynthetic process
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Disease: Rhizomelic Chondrodysplasia Punctata, Type 3
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Reference #:
O00116
(UniProtKB)
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Alt. Names/Synonyms: ADAP-S; ADAS; ADHAPS; ADPS; Aging-associated gene 5 protein; aging-associated protein 5; AGPS; ALDHPSY; Alkyl-DHAP synthase; alkyldihydroxyacetone phosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; alkylglycerone phosphate synthase; Alkylglycerone-phosphate synthase; DKFZp762O2215; FLJ99755; RCDP3
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Gene Symbols: AGPS
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Molecular weight:
72,912 Da
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Basal Isoelectric point:
6.99
Predict pI for various phosphorylation states
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