THAP7 Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors. Note: This description may include information from UniProtKB.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component:  chromosome; intracellular membrane-bounded organelle; nuclear membrane; nuclear speck; nucleus
Molecular Function:  C2H2 zinc finger domain binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding; metal ion binding; protein binding; protein N-terminus binding
Biological Process:  negative regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II
Reference #:  Q9BT49 (UniProtKB)
Alt. Names/Synonyms: MGC10963; THAP domain containing 7; THAP domain-containing protein 7; THAP7
Gene Symbols: THAP7
Molecular weight: 34,414 Da
Basal Isoelectric point: 9.54  Predict pI for various phosphorylation states
Select Structure to View Below

THAP7

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein