PPIB PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Belongs to the cyclophilin-type PPIase family. PPIase B subfamily. Note: This description may include information from UniProtKB.
Protein type: Chaperone; Cyclophilin; EC; Isomerase; RNA-binding; Secreted; Secreted, signal peptide
Chromosomal Location of mouse Ortholog: 9|9 C
Cellular Component:  cytoplasm; endoplasmic reticulum; endoplasmic reticulum chaperone complex; intracellular membrane-bounded organelle; nucleoplasm; perinuclear region of cytoplasm; smooth endoplasmic reticulum
Molecular Function:  cyclosporin A binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding; RNA polymerase binding
Biological Process:  bone development; neutrophil chemotaxis; positive regulation by host of viral genome replication; positive regulation by host of viral process; positive regulation of multicellular organism growth; protein folding; protein peptidyl-prolyl isomerization; protein stabilization
Reference #:  P24369 (UniProtKB)
Alt. Names/Synonyms: AA408962; AA553318; AI844835; Cph; Cphn; Cphn-2; Cphn2; Cyclophilin B; CyP-20; CyP-20b; CYP-S1; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; PPIase B; Ppib; Rotamase B; S-cyclophilin; SCYLP
Gene Symbols: Ppib
Molecular weight: 23,713 Da
Basal Isoelectric point: 9.56  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein